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神經科學

熱門產品

神經科學是針對神經系統的科學研究。神經元是神經系統中具備功能性的最小單元，各神經元相互連接形成網絡。這些特殊細胞具有被稱作“樹突和軸突”的纖細突出。信息通常以電信號或電化學信號的形式從一個神經元的軸突經由突觸傳遞到另一個神經元。

神經科學家采用諸如抗體和基因探針等工具分離鑒別與神經系統相關的蛋白質和其它分子。以下為分子識別的部分常見目標：

神經遞質（將信號從一個神經元經由突觸傳遞到另一個靶細胞的內源性化學物質）- 谷氨酸鹽、天冬氨酸鹽、多巴胺、腎上腺素、去甲腎上腺素、血清素、組胺等）
軸突導向分子和受體（通過吸引或排斥軸突尖端上的生長錐控制軸突生長方向）- 神經突起生長導向因子、髓鞘相關抑制因子、神經生長導向因子等
神經營養因子（誘導神經元生長、發育和發揮功能的蛋白質家族）- 神經素營養因子、膠質源性神經營養因子家族配體、神經生成細胞因子等
與神經干細胞發育相關的其它目標。

由神經系統問題導致的多種疾病。以下為部分最為常見的神經疾病抗體：

Neurodegeneration Antibodies

ALS Antibodies

Alzheimer Disease Ab

Huntington Disease Ab

Parkinsons Disease Ab

Multiple Sclerosis Ab

MPS Antibodies

Tay-Sachs Disease Ab

產品展示

	Axon Guidance Antibodies			Dopamine Antibodies
	570+ antibodies related to the guidance process of axons to reach the proper targets.			5 antibody arrays for apoptosis research.

	Neural Stem Cells Ab			Neuroscience Antibodies
	450+ antibodies for neural stem cells as the main phenotypes of the nervous system.			4120+ antibodies to expand your basic and clinical neuroscience research.

	Neurotransmitter Receptor			Neurotrophins Antibodies
	140+ antibodies for neurotransmitter receptors binding to neurotransmitters and hormones.			170+ antibodies for neurotrophins which regulate the development and function of neurons.

	Oligodendrocyte Ab			Semaphorin Antibodies
	60+ antibodies targeting oligodendrocytes which surround and insulate axons.			40+ antibodies for semaphorins that act as axonal growth cone guidance molecules.

	TARDBP Collection			IHC Ab Related to Neuroscience
	Antibodies, antibody pairs, proteins and siRNA to TARDBP.			1210+ antibodies for Immunohistochemistry related to neuroscience.

	Brain Tissue Slides
	Normal and cancerous brain tissue section slides for microscopic study of diseased state.

出版物

Hirano body - rich subtypes of Creutzfeldt-Jakob disease.
Martinez-Saez E, Gelpi E, Rey M, Ferrer I, Ribalta T, Botta-Orfila T, Nos C, Yague J, Sanchez-Valle R.Neuropathol Appl Neurobiol. 2011 Jul 5.
使用的亞諾法產品: TARDBP monoclonal antibody (M01), clone 2E2-D3

Neuropeptide Y and Neuropeptide Y Y5 Receptor Interaction Restores Impaired Growth Potential of Aging Bone Marrow Stromal Cells.
Igura K, Haider HK, Ahmed RP, Sheriff S, Ashraf M.Rejuvenation Res. 2011 May 19.
使用的亞諾法產品: NPY1R monoclonal antibody (M03), clone 2G2

Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: implications for Alzheimer's disease.
Nijholt DA, de Graaf TR, van Haastert ES, Oliveira AO, Berkers CR, Zwart R, Ovaa H, Baas F, Hoozemans JJ, Scheper W.Cell Death Differ. 2011 Jan 21.
使用的亞諾法產品: PSMB8 monoclonal antibody (M01), clone 1B3

Store-operated calcium entry modulates neuronal network activity in a model of chronic epilepsy.
Steinbeck JA, Henke N, Opatz J, Gruszczynska-Biegala J, Schneider L, Theiss S, Hamacher N, Steinfarz B, Golz S, Brustle O, Kuznicki J, Methner A.Exp Neurol. 2011 Aug 30.
使用的亞諾法產品: STIM1 monoclonal antibody (M01), clone 5A2

Increased Prothrombin, Apolipoprotein A-IV, and Haptoglobin in the Cerebrospinal Fluid of Patients with Huntington's Disease.
Huang YC, Wu YR, Tseng MY, Chen YC, Hsieh SY, Chen CM.PLoS One. 2011 Jan 31;6(1):e15809.
使用的亞諾法產品: APOA4 purified MaxPab mouse polyclonal antibody (B01P)

（點擊此處查閱更多與神經相關的出版物）

文獻

[海報] Axon Guidance.

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